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Experimental and Clinical Hepato-Gastroenterology

Offered by

Sapienza Università di Roma

Fields of Study

Medical, Pharmaceutical and Veterinary Medical Sciences

Working Languages

Italian, English


Experimental and Clinical Hepato-Gastroenterology

Research Areas

The curriculum in "Experimental and Clinical Hepatology" offers an interdisciplinary project-orientated postgraduate education for Medicine students as well as for students from Life Sciences disciplines. Students learn how to carry out an independent scientific work while focusing on their own 3-year research project, and, thus, gain a further qualification for the performance of tasks in research and teaching. The PhD Program will provide basics and methods in Medicine and Biology and their application on current research projects in the morphological/ultrastructural, molecular and clinical aspects of the hepatology. The scientific research projects are carried out in one of the Departments associated to the PhD Programme, allowing the integration between basic and clinical sciences. The ongoing interaction between students and the academic advisory board (which includes experts in anatomy, biology and hepatology) guarantees the scientific validity of the projects. The strong interaction between Clinical Departments and Basic Science Laboratories makes sure that the study projects are clinically oriented. Numerous collaborations with outstanding scientists and institutes also guarantees the scientific excellence of the programme. Short-term stays in other Italian or international institutions are also encouraged for full PhD students.

The University Institutions involved in the fellowship programme are:

1) The Texas A&M University System Health Science Center, College of Medicine, Temple, Texas; Prof. G. Alpini;

2) Department of Experimental Medicine, State University of 'L'Aquila'; Prof. P. Onori.

The PhD Program is mainly aimed at the acquisition of an interdisciplinary research approach in Experimental and Clinical Hepatology. During the 3-year period of the PhD Program students can apply the Basic Science research methods to the resolution of clinical issues in hepatology. Methods of advanced morphology, molecular and cellular biology, clinical hepatology are applied in the PhD Program.

The main research fields are:

a) proliferation and death cellular pathways in hepatocytes, cholangiocytes and mesenchymal cells involved in hepatic diseases; b) immunohistochemical and molecular prognostic markers in liver disease; c) morphological, ultrastructural and molecular features in liver and biliary pathophysiology and pathology; d) alterations of metabolism and coagulation in liver disease or secondary diseases involving the liver; e) therapeutic tools in liver and biliary congenital and acquired diseases.

The main formative objectives of the "Surgical pathophysiology and gastroenterology" curriculum are directed at the acquisition of scientific knowledge of surgery and gastroenterology in order to allow students to be able, by the end of the programme, to lead, analyze and autonomously perform activities in research projects. The initial part of the course will be devoted to the acquisition of the methodological aspects in experimental and clinical applied research, including statistical analysis. Subsequently students will focus on pathophysiology illness of the digestive system. Special consideration will be given to digestive neoplasia and their pathophysiology, following surgical interventions of the digestive system, and also after organ transplants.

PhD Full

Starting date:Nov 01, 2017
Duration:36 months

PhD Sandwich

Starting date: from Nov 01, 2017
Duration: from 3 to 12 months


Starting date: from Nov 01, 2017
Duration: from 3 to 12 months

Master research

Starting date: from Nov 01, 2017
Duration: from 3 to 6 months


Academic contact

Martina Vizzani

Institutional contact

Martina Vizzani